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Adrian J Wolstenholme Selected Research

Dirofilariasis

1/2019Macrocyclic lactone anthelmintic-induced leukocyte binding to Dirofilaria immitis microfilariae: Influence of the drug resistance status of the parasite.
12/2018Efficacy and side effects of doxycycline versus minocycline in the three-dose melarsomine canine adulticidal heartworm treatment protocol.
1/2016How do the macrocyclic lactones kill filarial nematode larvae?
9/2015The emergence of macrocyclic lactone resistance in the canine heartworm, Dirofilaria immitis.
11/2014Ivermectin-dependent attachment of neutrophils and peripheral blood mononuclear cells to Dirofilaria immitis microfilariae in vitro.

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Adrian J Wolstenholme Research Topics

Disease

6Paralysis (Palsy)
01/2018 - 10/2002
5Dirofilariasis
01/2019 - 11/2014
4Infections
07/2020 - 08/2004
3Filarial Elephantiasis (Lymphatic Filariasis)
12/2021 - 01/2016
2Onchocerciasis
12/2021 - 01/2016
1Loiasis
12/2021
1Filariasis
12/2021
1Nematode Infections
06/2021
1Muscle Spasticity (Spastic)
01/2018
1Ganglion Cysts (Ganglion)
04/2007
1Shock
10/2002
1Hypersensitivity (Allergy)
10/2002

Drug/Important Bio-Agent (IBA)

7Pharmaceutical PreparationsIBA
12/2021 - 09/2015
7LactonesIBA
07/2020 - 11/2014
5AnthelminticsIBA
01/2019 - 07/2003
3Ivermectin (Mectizan)FDA Link
06/2021 - 08/2004
3avermectinIBA
08/2004 - 10/2002
2glutamate-gated chloride channelsIBA
08/2004 - 07/2003
1emodepsideIBA
12/2021
1Albendazole (Albenza)FDA Link
01/2019
1Doxycycline (Periostat)FDA LinkGeneric
12/2018
1melarsomineIBA
12/2018
1Cholinergic ReceptorsIBA
01/2018
1Levamisole (Decaris)FDA Link
09/2015
1Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA
09/2015
1melanopsinIBA
04/2007
1TRPC6 Cation ChannelIBA
04/2007
1Ion Channels (Ion Channel)IBA
04/2007
1GABA-A Receptors (GABA(A) Receptor)IBA
07/2003
1gamma-Aminobutyric Acid (GABA)IBA
07/2003
1Chloride Channels (Chloride Channel)IBA
10/2002
1NeurotoxinsIBA
10/2002
1Ether (Diethyl Ether)IBA
10/2002
1Histamine (Histamine Dihydrochloride)FDA Link
10/2002

Therapy/Procedure

2Mass Drug Administration
12/2021 - 12/2018
1Chemoprevention
08/2004